Impact of Marijuana on the Adolescent Brain


Annual Review of Developmental Psychology: The Effects of Cannabis Use on the Development of Adolescents and Young Adults – January 2021

Association Between Friends Use of Nicotine and Cannabis and Intake of Both Substances among Adolescents – February 2021

The Effects of Marihuana on Adolescents and Young Adults – Kolansky & Moore, 1971 – February 2021

Young‐adult compared to adolescent onset of regular cannabis use: A 20‐year prospective cohort study of later consequences – January 2021. Cannabis users who began regular use in their teens had poorer later life outcomes than non‐using peers. The larger group who began regular cannabis use after leaving high school accounted for most cannabis‐related harms in adulthood. 


Adolescent Brain Cognitive Development (ABCD) Study – ongoing

Adolescent Δ 9-Tetrahydrocannabinol Exposure Selectively Impairs Working Memory – Nov. 2020

Cannabis and the Adolescent Brain – Jan. 2020

Can neuroimaging connect specific brain structures and functions with suicidal thoughts and behaviors? Apr. 2020

College students using more pot in legal states; binge drinking less – Jan. 2020

Familial factors may not explain the effect of moderate‐to‐heavy cannabis use on cognitive functioning in adolescents: a sibling‐comparison study – Sept. 2020

National Institute on Drug Abuse for Teens – Updated Jul. 2020

Pediatric Chest Radiographic and CT Findings of Electronic Cigarette or Vaping Product Use–associated Lung Injury – Mar. 2020


A Deep Dive into Adolescent Development – June 2019

A Population-Based Analysis of the Relationship Between Substance Use and Adolescent Cognitive Development – Feb. 2019

Age-related differences in the impact of cannabis use on the brain
and cognition: a systematic review
– January 2019

Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood – Feb. 2019

Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence – March 2019

Early, heavy, and chronic cannabis use does have substantive negative effects on the brain – Oct. 2019

FOR YOUR CONSIDERATION: BRAIN PRO DR. AMEN ON CANNABIS + THE DEVELOPING BRAIN – Oct. 2019. In his book Change Your Brain, Change Your Grades, Dr. Amen unpacks the reasons why students need to avoid addictive substances like cannabis. They change your brain in ways that make it harder for you to learn new things, memorize class material and maintain good study habits. They are likely to change your grades but in the wrong direction.

Growing up high: Understanding the impacts of adolescent cannabis use on mental health and brain development – Aug. 2019

Growing Up High PDF – Jun. 2019

Impact of neuroimmune activation induced by alcohol or drug abuse on adolescent brain development – Oct. 2019

Is the Adolescent Brain at Greater Vulnerability to the Effects of Cannabis? A Narrative Review of the Evidence – August 2020

Longitudinal Alterations in Prefrontal Resting Brain Connectivity in Non-Treatment-Seeking Young Adults With Cannabis Use Disorder – July 2019

Marijuana use among adolescents is associated with deleterious alterations in mature BDNF – Jan. 2019


Adolescent neurocognitive development and impacts of substance use: Overview of the adolescent brain cognitive development (ABCD) baseline neurocognition battery – August 2018

Cannabis Involvement and Neuropsychological Performance: Findings from the Human
Connectome Project
– Oct. 2018

How Marijuana May Damage Teenage Brains in Study Using Genetically Vulnerable Mice – Dec. 2018

One Month of Abstinence from Cannabis Improves Memory in Adolescents, Young Adults – Science Daily Oct. 2018

Synthetic Cannabinoids: Spice, K2 and similar marijuana-like substances – Dec. 2018

What are the effects of increasing cannabis potency on adolescent health? – Lancet 2018

2017 or later

Adolescent Brain Development and Drug Abuse – June 2008

Adolescent Cannabis Use and Psychosis: Epidemiology and Neurodevelopmental Models – 2010

Adverse Effects of Cannabis on Adolescent Brain Development: A Longitudinal Study – March 2017

Biology of Addiction: Drugs and Alcohol Can Hijack Your Brain – Oct. 2015

Cannabis and Adolescent Brain Development – 2015

Cannabis Exposure May Lead to Psychosis – Jan. 2015

Cannabis Use and Later Life Outcomes – Jun. 2008

Insights into Human Behavior from Lesions to the Prefrontal Cortex – Sept. 2014

Longitudinal Development of Human Brain Wiring Continues from Childhood into Adulthood – July 2011

Longitudinal Changes in White Matter Microstructure After Heavy Cannabis Use – May 2015

Marijuana and the developing brain – Nov. 2015

Persistent Cannabis Users Show Neuropsychological Decline from Childhood to Midlife – July 2012

Recreational marijuana use impacts white matter integrity and subcortical (but not cortical) morphometry – Jun. 2016

Teens who smoke pot at risk for later schizophrenia, psychosis – Mar. 2011

The Addictive Brain: All Roads Lead to Dopamine – April 2012

The effects of Δ9-tetrahydrocannabinol on the dopamine system – May 2017

Why Teens Are Impulsive, Addiction-Prone And Should Protect Their Brains – Jan. 2015

Youth and marijuana: Youth are at special risk for harm – Jun. 2016